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Variations of normal reactions that are not considered adverse events can include:
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Local satellite lesions(*) (that are normal in appearance) |
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Lymphangitis |
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Local edema |
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Robust take (†) (intense inflammation surrounding the papule) |
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The frequency of satellite lesions
varies from study to study (2.4 to 6.6 %). |
| † |
This normal consequence of vaccination is a viral cellulitis at the vaccination site of varying degree that peaks at about 7-10 days following vaccination. A robust take or larger amount of inflammation surrounding the site, is often confused with
bacterial infection. |
Management
None of these expected variations of normal reactions require any treatment other than symptomatic relief.
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