Within a week after the onset of a vaccination reaction, lesions appear on unimmunized skin and appear to derive from viremia, not inoculation by transfer. Each takes the form of a primary vaccination, but is usually much smaller in size, and undergoes rapid evolution to scarring.
Lesions may occur on any part of the body, most often on the trunk and abdomen, less commonly on the face and limbs. Lesions may occur on the palms and soles. In rare cases, a profuse rash occurs and may be confluent in nature. Rarely, lesions may recur at 4-6 week intervals for as long as one year.
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