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Erythema Multiforme: Frequency & Susceptible Populations

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Click here to Zoom Close-up of vaccination site with intense surrounding erythematous papules and plaques coalescent surrounding vaccination site
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A variety of rashes occur in a large number of vaccinees 1-2 weeks after vaccination.



Erythema Multiforme (EM) Cases per 1,000,000 Primary Vaccinations(*)

Age (yrs)

1968 National
Survey(†)

1968 10-State
Survey(§)

1-4 N/A 164.0
5-19 N/A 91.7
>20 N/A 30.3
Totals >1 yr N/A 131.3

* Numbers rounded to the nearest tenth, total number of vaccinations estimated in both studies. Observations missing age were distributed according to the existing age distribution for EM.
EM case rates not reported in this study.
§ Case sources include: Physician reporting via survey in 10 states with active case information follow-up and chart review for post-vaccinial encephalitis and vaccinia necrosum reports.

Recent Studies

Recent studies indicate that 5.6-14.3 percent of adult vaccinees develop rashes at sites other than the vaccination. 







 
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