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Post-Vaccinial Encephalitis: Clinical Manifestations

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Illustration of the human brain and upper spinal cord

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Encephalitis usually occurs 10-14 days after vaccination. It is difficult to delineate the clinical spectrum because of the potential confusion with other causes of encephalitis in reported cases.

Headache, vomiting, drowsiness and fever are the first symptoms observed and may be all that is seen in mild cases with rapid recovery. In more severe cases, symptoms progress to include paralysis, incontinence, urinary retention, and various forms of convulsions. 

Death can occur suddenly, usually within a week of onset of symptoms.

Many patients recover completely without discernible residua. Some patients experience a variety of neurologic sequelae.

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