More Examples of Major or "Take" Reactions to Smallpox Vaccination
Formation by days 6-8 post-vaccination of a papule, vesicle, ulcer, or crusted central lesion, surrounded by an area of induration signifies a response to vaccination; this event is referred to as a major reaction or a "take," and usually results in a scar.
Source: Smallpox Vaccination and Adverse Events Training Module, Logical Images
Page last reviewed February 7, 2007
Page last modified February 21, 2003
Content Source:
- Coordinating Center for Infectious Diseases (CCID)
National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID)
Division of Bioterrorism Preparedness and Response (DBPR)