Smallpox: Diagnosis/Evaluation
Information for the public can be found on the Smallpox Disease page.
Highlights
- Risk Evaluation Algorithm: Evaluate a Rash Illness Suspicious for Smallpox
- Acute, Generalized Vesicular or Pustular Rash Illness Testing Protocol in the US
- Smallpox Response Plan & Guidelines
Diagnosis Tools
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Risk Evaluation Algorithm: Evaluate a Rash Illness Suspicious for Smallpox
Use this online form to instantly evaluate a rash illness suspicious for smallpox -
Poster: Evaluating Patients for Smallpox
Evaluation protocol, risk evaluation, chickenpox-smallpox comparison, common conditions comparison...
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Worksheet: Evaluating Patients for Smallpox
(182 KB/4 pages)
Standard worksheet for evaluating patients for smallpox. Use this investigation form for collecting information on cases of acute, generalized vesicular or pustular rash illness & to classify risk of smallpox using CDC criteria outlined in the poster ("Evaluating Patients for Smallpox").
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Smallpox
Case Definitions
Includes clinical case definition, lab criteria for confirmation, case classification, clinical types of variola major
Laboratory Testing
- Acute, Generalized Vesicular or Pustular Rash Illness Testing Protocol in the US (2.17 MB/5 pages)
Protocol developed to illustrate types of lab testing for patients with acute, generalized vesicular or pustular rash illness
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Negative Staining Electron Microscopic Protocol for Rash Illness (458 KB/8 pages)
Instructions for laboratorians
Images
Training
References
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Consensus Statement: Smallpox as a Biological Weapon: Medical & Public Health Management
JAMA 1999 Jun 9;281(22):2127-2137.
PDF (361 KB/11 pages)
Abstract
Concise, bulleted summary of the full article
PDF (165 KB/6 pages)Jun 9, 1999 -
Smallpox Response Plan & Guidelines
Provides direction to state & local health officials for responding to a smallpox emergency.
- Isolation & Quarantine Guidelines (Guide C)
From the Smallpox Response Plan and Guidelines (Version 3.0)
(22 pages total, broken into 2 sections)
PDF (236 KB/14 pages)
PDF (174 KB/8 pages) -
Specimen Collection Guidelines (Guide D)
From the Smallpox Response Plan and Guidelines (Version 3.0)
PDF (239 KB/12 pages) -
Epidemiology and Prevention
of Vaccine-Preventable Diseases: Smallpox Chapter (963 KB/24 pages)
The Pink Book
January 2005 -
Recognition of Illness Associated with the Intentional Release of a Biologic Agent
MMWR 2001 Oct 19;50(41):893-897.
PDF (168 KB/20 pages)
Historical Archives
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