Smallpox: Diagnosis/Evaluation
Information for the public can be found on the Smallpox Disease page.
Highlights
- Risk Evaluation Algorithm: Evaluate a Rash Illness Suspicious for Smallpox
- Acute, Generalized Vesicular or Pustular Rash Illness Testing Protocol in the US
- Smallpox Response Plan & Guidelines
Diagnosis Tools
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Risk Evaluation Algorithm: Evaluate a Rash Illness Suspicious for Smallpox
Use this online form to instantly evaluate a rash illness suspicious for smallpox -
Poster: Evaluating Patients for Smallpox
Evaluation protocol, risk evaluation, chickenpox-smallpox comparison, common conditions comparison...
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Worksheet: Evaluating Patients for Smallpox
(182 KB/4 pages)
Standard worksheet for evaluating patients for smallpox. Use this investigation form for collecting information on cases of acute, generalized vesicular or pustular rash illness & to classify risk of smallpox using CDC criteria outlined in the poster ("Evaluating Patients for Smallpox").
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Smallpox
Case Definitions
Includes clinical case definition, lab criteria for confirmation, case classification, clinical types of variola major
Laboratory Testing
- Acute, Generalized Vesicular or Pustular Rash Illness Testing Protocol in the US (2.17 MB/5 pages)
Protocol developed to illustrate types of lab testing for patients with acute, generalized vesicular or pustular rash illness
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Negative Staining Electron Microscopic Protocol for Rash Illness (458 KB/8 pages)
Instructions for laboratorians
Images
Training
References
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Consensus Statement: Smallpox as a Biological Weapon: Medical & Public Health Management
JAMA 1999 Jun 9;281(22):2127-2137.
PDF (361 KB/11 pages)
Abstract
Concise, bulleted summary of the full article
PDF (165 KB/6 pages)Jun 9, 1999 -
Smallpox Response Plan & Guidelines
Provides direction to state & local health officials for responding to a smallpox emergency.
- Isolation & Quarantine Guidelines (Guide C)
From the Smallpox Response Plan and Guidelines (Version 3.0)
(22 pages total, broken into 2 sections)
PDF (236 KB/14 pages)
PDF (174 KB/8 pages) -
Specimen Collection Guidelines (Guide D)
From the Smallpox Response Plan and Guidelines (Version 3.0)
PDF (239 KB/12 pages) -
Epidemiology and Prevention
of Vaccine-Preventable Diseases: Smallpox Chapter (963 KB/24 pages)
The Pink Book
January 2005 -
Recognition of Illness Associated with the Intentional Release of a Biologic Agent
MMWR 2001 Oct 19;50(41):893-897.
PDF (168 KB/20 pages)
Historical Archives
- Content source: National Center for Environmental Health (NCEH)/Agency for Toxic Substances and Disease Registry (ATSDR), Office of Noncommunicable Diseases, Injury and Environmental Health, National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), National Center on Birth Defects and Developmental Disabilities (NCBDDD)
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