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Plague  Lesson 7
 Veterinarian Issues

Plague Treatment

  • In addition to thorough physical examination, radiographs of the chest should be done to check for the possibility of plague pneumonia.
  • Antibiotic therapy should be started promptly.
  • Streptomycin is the treatment of choice, but is difficult to obtain. Alternatives include:
    • Gentamicin (2-3 mg/kg tid, IM or SQ [bacteriocidal])
    • Doxycycline (5 mg/kg bid, PO [bacteriostatic])
    • Tetracycline (22 mg/kg tid, PO [bacteriostatic])
    • Chloramphenicol (50 mg/kg bid, PO [bacteriostatic])
  • Sulfonamides can be tried, but only if other drugs are not available.
  • Infected animals receiving parenteral antibiotics may be switched to oral therapy upon clinical improvement.
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Page last reviewed February 12, 2007
Page last modified September 7, 2004

  • Content source: CDC Emergency Risk Communication Branch (ERCB), Division of Emergency Operations (DEO), National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
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