Laboratory Specimen Collection – Procedures
- Lymph node aspirates
- Due to the large amount of surrounding edema, care must
be taken to be sure the bubo itself is aspirated.
- If little or no fluid can be aspirated, 1 cc of non-bacteriostatic
saline solution can be injected into the bubo and then aspirated
back into the syringe.
- Acute and convalescent serum samples of 0.5 ml should be
collected at least 14 days apart.
- Note that serology is only of use for retrospective confirmation
of diagnosis; acute serology alone is of no benefit, since
early in the disease patients are often seronegative.
- Pharyngeal Swab
- If there is evidence of plague pneumonia, pharyngeal swab
should be made, using culturettes.