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Plague  Lesson 4
 Laboratory Issues - Clinicians

Pneumonic Plague - Laboratory Testing

  • Consistent with the systemic inflammatory response syndrome.
    • Leukocyte count - elevated.
    • Differential - neutrophil predominance, including immature forms.
    • Platelets - may be normal or low.
    • WBCs 15,000-25,000/µl, left shift.
    • AST, ALT, and bilirubin elevated.
  • Coagulation abnormalities
    • Fibrin split products.
    • DIC possible.
    • Increased fibrin degradation products.
    • Hypofibrinogenemia.
    • Prolongation of the prothrombin time (PT) and partial thromboplastin time (PTT).
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Page last reviewed February 12, 2007
Page last modified September 7, 2004

  • Content source: Division of Bioterrorism Preparedness and Response (DBPR), National Center for Preparedness, Detection, and Control of Infectious Diseases (NCPDCID), Coordinating Center for Infectious Diseases (CCID)
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