The endotoxemia and systemic inflammatory response syndrome associated
with septicemic plague must be differentiated from any bacterial
or viral invasion of the body that can cause septicemic shock.
- Incubation Period- Occurs when
plague bacteria multiply in the blood. Septicemic plague is
more common than primary pneumonic plague and is usually associated
with hunters skinning infected animals.
- Symptoms- Acute onset of fever,
chills, prostration, abdominal pain, nausea, and vomiting.
- Progression of Disease- Pupura and
disseminated intravascular coagulation (DIC) are quite common
with plague sepsis. Eventual amputation of fingers, toes, or
feet is not uncommon.