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Plague  Lesson 3
  Differential Diagnosis

Bubonic Plague

Disease Characteristics
Primary genital herpes
  • Herpes lesions present in genital area.
  • Adenitis occurs in the inguinal region.
  • Although patients may be ill (fever, headache), severe systemic toxicity not present.
Primary or secondary syphilis (Treponema pallidum)
  • Enlarged lymph nodes in the inguinal region.
  • Lymph nodes generally painless.
  • Chancre may be noted with primary syphilis.
Strangulated inguinal hernias
  • Evidence of bowel involvement.

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Page last reviewed February 12, 2007
Page last modified September 7, 2004

  • Content source: CDC Emergency Risk Communication Branch (ERCB), Division of Emergency Operations (DEO), National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
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