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Plague  Lesson 3
 Differential Diagnosis

Bubonic Plague

  • Progression of Disease- If bubonic plague is not treated, the bacteria can spread through the bloodstream causing septicemia or it can infect the lungs, causing a secondary case of pneumonic plague. Rarely, it can progress to meningitis.
    • Individuals with bubonic plague may experience prostration, restlessness, confusion, delirium, and a lack of coordination.
    • Some patients may experience intestinal discomfort like nausea, vomiting, diarrhea, and/or abdominal pain.
    • The lymph nodes may begin to suppurate during the second week.
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Animation of lymph node suppuration.
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Page last reviewed February 12, 2007
Page last modified September 7, 2004

  • Content source: CDC Emergency Risk Communication Branch (ERCB), Division of Emergency Operations (DEO), National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
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